Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RXRB | P28702 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717358 | 0.94 | LMNA (0.60) | APPMAOBRXRARXRBFFAR1 | |
| SCHEMBL419232 | 0.92 | MAOB (0.69) | APPMAOBRXRARXRBFFAR1 | |
| SCHEMBL891493 | 0.90 | FFAR1 (0.69) | APPMAOBFFAR1FFAR4PPARG | |
| SCHEMBL228292 | 0.88 | LMNA (0.67) | APPMAOBRXRARXRBFFAR1 | |
| SCHEMBL4953 | 0.86 | LMNA (0.64) | APPMAOBRXRARXRBFFAR1 | |
| SCHEMBL11849334 | 0.86 | LMNA (0.69) | APPMAOBFFAR1FFAR4PPARG | |
| SCHEMBL2399080 | 0.86 | APP (0.80) | APPMAOBRXRARXRBFFAR1 | |
| SCHEMBL11839266 | 0.85 | APP (0.62) | APPMAOBRXRARXRBFFAR1 | |
| SCHEMBL5538712 | 0.84 | LMNA (0.72) | APPMAOBFFAR1FFAR4CA12 | |
| SCHEMBL7665986 | 0.83 | MCL1 (0.60) | APPMAOBRXRARXRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987102-A | PHENOXY (BENZYLOXY) BENZENE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | claimed |