Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12948213 | 0.81 | ALDH1A1 (0.37) | CYP2C19GAALMNACYP3A4TSHR | |
| SCHEMBL28327621 | 0.73 | HSD17B10 (0.46) | CYP2C19GAALMNAKDM4ETSHR | |
| SCHEMBL24835551 | 0.72 | ALDH1A1 (0.32) | ALDH1A1MEN1USP2MAPTHPGD | |
| SCHEMBL11528640 | 0.72 | THRB (0.47) | CYP2C19LMNATSHRALDH1A1TP53 | |
| SCHEMBL19153385 | 0.69 | MEN1 (0.32) | ALDH1A1MEN1USP2MAPTHPGD | |
| SCHEMBL20124876 | 0.69 | CYP2C19 (0.30) | CYP2C19 | |
| SCHEMBL12428880 | 0.69 | — | — | |
| SCHEMBL11447658 | 0.69 | LPL (0.31) | LPLLIPG | |
| SCHEMBL8985724 | 0.69 | — | — | |
| SCHEMBL11400531 | 0.68 | CYP2C19 (0.36) | CYP2C19GAANPSR1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931270-A | Process for producing 2-thia substituted 1,4 diones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-01-06 | — | — | US | disclosed |