Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9405219 | 0.73 | — | — | |
| SCHEMBL571307 | 0.73 | — | — | |
| SCHEMBL9813481 | 0.73 | — | — | |
| SCHEMBL5894733 | 0.73 | — | — | |
| SCHEMBL25218064 | 0.71 | — | — | |
| SCHEMBL3482296 | 0.69 | ALDH1A1 (0.40) | TSHRDAONAPRTALDH1A1CES2 | |
| SCHEMBL38902 | 0.69 | ALDH1A1 (0.40) | TSHRDAONAPRTALDH1A1CES2 | |
| SCHEMBL9729956 | 0.67 | TP53 (0.38) | TSHRDAONAPRTALDH1A1CES2 | |
| SCHEMBL1494196 | 0.67 | TSHR (0.33) | TSHRDAONAPRTALDH1A1ALOX15 | |
| SCHEMBL8688082 | 0.67 | TSHR (0.38) | TSHRDAONAPRTALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1062 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150726-A1 | THERMOSOFTENING THERMALLY-CONDUCTIVE MEMBER | 信越化学工業株式会社 | 2024-07-18 | — | — | WO | claimed |
| WO-2024127889-A1 | THERMALLY CONDUCTIVE COMPOSITE SILICONE RUBBER SHEET | 信越化学工業株式会社 | 2024-06-20 | — | — | WO | claimed |
| EP-4368658-A1 | ORGANOPOLYSILOXANE AND PRODUCTION METHOD THEREFOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-05-15 | — | — | EP | claimed |
| CN-117616068-A | Organopolysiloxane and method for producing same | 信越化学工业株式会社 | 2024-02-27 | — | — | CN | claimed |
| EP-3867292-B1 | ASPARTIC ACID ESTER-FUNCTIONAL POLYSILOXANES, THEIR PREPARATION AND USE THEREOF | MOMENTIVE PERFORMANCE MAT GMBH (DE) | 2023-12-06 | — | — | EP | claimed |
| CN-113195579-B | Aspartate-functional polysiloxanes, their preparation and their use | 迈图高新材料有限责任公司 | 2023-05-02 | — | — | CN | claimed |
| WO-2023282115-A1 | ORGANOPOLYSILOXANE AND PRODUCTION METHOD THEREFOR | 信越化学工業株式会社 | 2023-01-12 | — | — | WO | claimed |
| US-11542369-B2 | Aspartic acid ester-functional polysiloxanes, their preparation and use thereof | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2023-01-03 | — | — | US | claimed |
| US-20210363307-A1 | ASPARTIC ACID ESTER-FUNCTIONAL POLYSILOXANES, THEIR PREPARATION AND USE THEREOF | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2021-11-25 | — | — | US | claimed |
| CN-113195579-A | Aspartate-functional polysiloxanes, their preparation and their use | 迈图高新材料有限责任公司 | 2021-07-30 | — | — | CN | claimed |
| EP-0501156-B1 | Method for enhancing the flame retardance of polyphenylene ethers | GEN ELECTRIC (US) | 1995-04-05 | — | — | EP | claimed |
| US-5217633-A | LOW-TEMPERATURE LUBRICATING OIL | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | claimed |
| US-5169887-A | Gives intumescent char after combustion; blending with polysiloxanes having a phenylsilanediol monomer | GENERAL ELECTRIC COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| EP-0510873-A2 | Self-reinforcing siloxane elastomers | DOW CORNING CORPORATION (US) | 1992-10-28 | — | — | EP | claimed |
| EP-0501156-A2 | Method for enhancing the flame retardance of polyphenylene ethers | GENERAL ELECTRIC COMPANY (US) | 1992-09-02 | — | — | EP | claimed |
| US-5139816-A | UV radiation curing of epoxy- or vinyl-functional diorganopolysiloxanes | GENERAL ELECTRIC COMPANY (US) | 1992-08-18 | — | — | US | claimed |
| US-4155864-A | ENDCAPPED POLYDIMETHYLSILOXANE AND MINOR AMOUNT OF ANOTHER POLYSILOXANE; DIELECTRIC FLUIDS IN ELECTRICAL APPARATUS | UNION CARBIDE CORPORATION (US) | 1979-05-22 | — | — | US | claimed |
| US-4056492-A | PROCESS FOR THE PRODUCTION OF A BODIED SILICONE RESIN WITHOUT THE USE OF A CATALYST | GENERAL ELECTRIC COMPANY (US) | 1977-11-01 | — | — | US | claimed |
| US-4001168-A | Transparent storage-stable polysiloxanes which cross-link under atmospheric conditions | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | claimed |
| US-3959563-A | Method for rendering vitreous surfaces water repellant and dirt deposit resistant and articles produced thereby | GENERAL ELECTRIC COMPANY (US) | 1976-05-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542369-B2 | Aspartic acid ester-functional polysiloxanes, their preparation and use thereof | GLUL, GABRE, DNPEP | TSHR 4826/4885DAO 37/4885NAPRT 3094/4885 |
| US-20210363307-A1 | ASPARTIC ACID ESTER-FUNCTIONAL POLYSILOXANES, THEIR PREPARATION AND USE THEREOF | GLUL, GABRE, DNPEP | TSHR 4826/4885DAO 37/4885NAPRT 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.