Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 5/20 | 0.35 |
| ▸ | CES1 | P23141 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766058 | 0.80 | TP53 (0.35) | TP53PSIP1CES2CES1TSHR | |
| SCHEMBL8688082 | 0.74 | TSHR (0.38) | CES2CES1TSHRALDH1A1MEN1 | |
| SCHEMBL8381981 | 0.72 | TP53 (0.41) | TP53PSIP1CES2CES1TSHR | |
| SCHEMBL416585 | 0.72 | TP53 (0.41) | TP53PSIP1CES2CES1TSHR | |
| SCHEMBL80927 | 0.72 | TP53 (0.41) | TP53PSIP1CES2CES1TSHR | |
| Fluoride SCHEMBL27660896 | 0.70 | TP53 (0.39) | TP53PSIP1CES2CES1TSHR | |
| Water SCHEMBL20720558 | 0.70 | TP53 (0.39) | TP53PSIP1CES2CES1TSHR | |
| Fluoride SCHEMBL27660670 | 0.70 | TP53 (0.39) | TP53PSIP1CES2CES1TSHR | |
| SCHEMBL2229742 | 0.70 | TP53 (0.39) | TP53PSIP1CES2CES1TSHR | |
| SCHEMBL571307 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190263765-A1 | SYNERGISTIC ANTICOAGULANT COMPOSITION | WISYS TECH FOUNDATION INC (US) | 2019-08-29 | — | — | US | claimed |
| US-4155864-A | ENDCAPPED POLYDIMETHYLSILOXANE AND MINOR AMOUNT OF ANOTHER POLYSILOXANE; DIELECTRIC FLUIDS IN ELECTRICAL APPARATUS | UNION CARBIDE CORPORATION (US) | 1979-05-22 | — | — | US | claimed |
| EP-3689891-B1 | COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION | UNIV KYUSHU NAT UNIV CORP (JP) | 2023-03-01 | — | — | EP | disclosed |
| US-20200247957-A1 | COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2020-08-06 | — | — | US | disclosed |
| EP-3689891-A1 | COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION | Kyushu University, National University Corporation (JP) | 2020-08-05 | — | — | EP | disclosed |
| CN-111132990-A | Cobalt complex, process for producing the same, and catalyst for hydrosilylation | 国立大学法人九州大学 | 2020-05-08 | — | — | CN | disclosed |
| US-5106934-A | High tear strength | GENERAL ELECTRIC COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0455132-A2 | Heat curable silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4155864-A | ENDCAPPED POLYDIMETHYLSILOXANE AND MINOR AMOUNT OF ANOTHER POLYSILOXANE; DIELECTRIC FLUIDS IN ELECTRICAL APPARATUS | UNION CARBIDE CORPORATION (US) | 1979-05-22 | — | — | US | disclosed |
| US-4146549-A | CATALYSTS FOR POLYMERIZATION OF ETHYLENE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-03-27 | — | — | US | disclosed |
| US-4145505-A | BIS(O-CHLOROBENZOYL)PEROXIDE AS CROSSLINKER | AKZONA INCORPORATED (US) | 1979-03-20 | — | — | US | disclosed |
| US-4027089-A | ORGANO-ALUMINUM-MAGNESIUM COMPLEX, SILOXANE AND HALOGENATED TRANSITION METAL COMPOUND CATALYST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1977-05-31 | — | — | US | disclosed |
| US-3989878-A | COMPLEX OF ORGANOMETALLICS AND SILOXANES | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190263765-A1 | SYNERGISTIC ANTICOAGULANT COMPOSITION | PROC, F2, VKORC1 | TP53 4147/4885PSIP1 2172/4885CES2 1994/4885 |
| US-20200247957-A1 | COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION | OR51E2, WEE2, SLC39A11 | TP53 2972/4885PSIP1 36/4885CES2 824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.