Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 8/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850528 | 0.83 | SRC (0.46) | SRCIDO1TDO2ESR1ESR2 | |
| SCHEMBL28427166 | 0.72 | IDO1 (0.52) | IDO1TDO2ESR1ESR2PDCD1 | |
| SCHEMBL2997923 | 0.69 | ESR1 (0.52) | IDO1TDO2ESR1ESR2PDCD1 | |
| SCHEMBL10454830 | 0.68 | IDO1 (0.44) | SRCIDO1TDO2ESR1ESR2 | |
| SCHEMBL5153744 | 0.67 | SRC (0.57) | SRCESR1ESR2PDCD1CD274 | |
| SCHEMBL51763 | 0.67 | ESR1 (0.52) | SRCIDO1TDO2ESR1ESR2 | |
| Hydroquinone SCHEMBL27782761 | 0.65 | GAA (0.50) | ESR1ESR2LMNACA12CA1 | |
| Hydroquinone SCHEMBL27782760 | 0.65 | GAA (0.50) | ESR1ESR2LMNACA12CA1 | |
| SCHEMBL25316271 | 0.65 | ESR1 (0.54) | SRCESR1ESR2PDCD1CD274 | |
| SCHEMBL10980126 | 0.65 | ENPP2 (0.50) | SRCESR1ESR2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932481-A | ANTILIPEMIC | SHANDOZ, INC. (US) | 1976-01-13 | — | — | US | disclosed |