Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106826 | 0.89 | IDO1 (0.47) | ESR1ESR2PDCD1CD274IDO1 | |
| Methacrylic Acid SCHEMBL9703416 | 0.82 | ESR1 (0.41) | ESR1ESR2PDCD1CD274IDO1 | |
| Acrylic Acid SCHEMBL9704013 | 0.82 | ALDH5A1 (0.41) | ESR1ESR2PDCD1CD274IDO1 | |
| SCHEMBL8732821 | 0.81 | GRIN1 (0.38) | ESR1ESR2PDCD1CD274IDO1 | |
| SCHEMBL5142966 | 0.79 | ESR1 (0.52) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL28427166 | 0.78 | IDO1 (0.52) | ESR1ESR2PDCD1CD274IDO1 | |
| SCHEMBL21769395 | 0.77 | ESR1 (0.50) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL303515 | 0.77 | ESR1 (0.56) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL23296602 | 0.76 | IDO1 (0.46) | IDO1TDO2LMNACYP1A2CHRM2 | |
| SCHEMBL791847 | 0.76 | MLKL (0.49) | MAPTTDP1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222059-B1 | IMPROVED RADIATION-HARDENABLE DILUENTS | HENKEL CORPORATION (a Delaware corp.) (US) | 1992-07-08 | — | — | EP | claimed |
| US-8481238-B2 | Electrophotographic photoreceptors, electrophotographic photoreceptor cartridge, and image-forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20100183332-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTORS, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |