Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850273 | 1.00 | LCK (0.59) | LCKOPRK1HSD17B10ALDH1A1THRB | |
| SCHEMBL11849660 | 0.94 | LCK (0.65) | LCKOPRK1HSD17B10ALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL11684930 | 0.93 | LCK (0.64) | LCKOPRK1HSD17B10ALDH1A1THRB | |
| SCHEMBL11860286 | 0.91 | EGFR (0.55) | LCKOPRK1HSD17B10ALDH1A1THRB | |
| SCHEMBL11852840 | 0.91 | EGFR (0.55) | LCKOPRK1HSD17B10ALDH1A1THRB | |
| SCHEMBL11861185 | 0.90 | YARS1 (0.53) | LCKOPRK1HSD17B10KDM4EUSP2 | |
| SCHEMBL11857396 | 0.90 | YARS1 (0.53) | LCKOPRK1HSD17B10KDM4EUSP2 | |
| SCHEMBL17359622 | 0.90 | LCK (0.58) | LCKOPRK1HSD17B10ALDH1A1THRB | |
| SCHEMBL7139809 | 0.89 | OPRK1 (0.69) | OPRK1HSD17B10ALDH1A1THRBCYP2C9 | |
| SCHEMBL30581396 | 0.89 | OPRK1 (0.69) | OPRK1HSD17B10ALDH1A1THRBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |