Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.56 |
| ▸ | CPA3 | P15088 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21998516 | 1.00 | ANPEP (0.56) | ANPEPCPA3FOLH1TRPA1CYP1A2 | |
| SCHEMBL19710215 | 1.00 | ANPEP (0.56) | ANPEPCPA3FOLH1TRPA1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL27529792 | 0.87 | CPA3 (0.53) | ANPEPCPA3FOLH1TRPA1CYP1A2 | |
| SCHEMBL1833635 | 0.85 | TRPA1 (0.55) | TRPA1CYP1A2EPHX1 | |
| Ammonia Solution, Strong SCHEMBL29021310 | 0.82 | TRPA1 (0.53) | TRPA1CYP1A2EPHX1 | |
| SCHEMBL3091848 | 0.80 | TRPA1 (0.52) | TRPA1CYP1A2EPHX1 | |
| SCHEMBL3091836 | 0.80 | TRPA1 (0.52) | TRPA1CYP1A2EPHX1 | |
| SCHEMBL5105980 | 0.80 | TRPA1 (0.52) | CPA3TRPA1CYP1A2EPHX1MAPK1 | |
| SCHEMBL25158 | 0.78 | TRPA1 (0.56) | TRPA1CYP1A2EPHX1 | |
| SCHEMBL2212544 | 0.78 | TRPA1 (0.56) | TRPA1CYP1A2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932487-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-13 | — | — | US | disclosed |