Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11725972 | 0.84 | KDM4C (0.47) | AOC3KDM4CCDK2MAOBPOLB | |
| SCHEMBL28799249 | 0.82 | ABCG2 (0.46) | ABCG2AOC3KDM4CGSK3BAURKA | |
| SCHEMBL30575803 | 0.82 | ABCG2 (0.46) | ABCG2AOC3KDM4CGSK3BAURKA | |
| SCHEMBL461998 | 0.82 | ITGB2 (0.50) | CHRNB4CHRNA3KDM4ELMNAGAA | |
| SCHEMBL13517569 | 0.79 | ABCG2 (0.52) | ABCG2KDM4CCYP3A4CDK2PKM | |
| SCHEMBL9534791 | 0.78 | KDM4E (0.42) | CHRNB4CHRNA3PKMMAOBKDM4E | |
| SCHEMBL9535019 | 0.78 | KDM4E (0.42) | CHRNB4CHRNA3MAOBKDM4ELMNA | |
| SCHEMBL7594061 | 0.76 | ABCG2 (0.55) | ABCG2GSK3BPKMTSHREED | |
| SCHEMBL14950291 | 0.75 | AOC3 (0.44) | ABCG2AOC3KDM4CCYP3A4PKM | |
| SCHEMBL2265157 | 0.75 | AOC3 (0.44) | ABCG2AOC3KDM4CCYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020534-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-02-23 | — | — | WO | claimed |
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | BASF SE (DE) | 2019-03-05 | — | — | US | claimed |
| US-20170100337-A1 | Naltrexone hydrochloride compositions | PURDUE PHARMA LP (US) | 2017-04-13 | — | — | US | claimed |
| US-20160317456-A1 | PHARMACEUTICAL COMPOSITIONS | PURDUE PHARMA LP (US) | 2016-11-03 | — | — | US | claimed |
| EP-1482912-B1 | NALTREXONE HYDROCHLORIDE COMPOSITIONS | EURO CELTIQUE SA (LU) | 2011-05-25 | — | — | EP | claimed |
| US-7771734-B2 | Process to color and permanently restructure hair | WELLA AG (DE) | 2010-08-10 | — | — | US | claimed |
| EP-1655056-B1 | Process to colour and permanently restructure hair | WELLA AG (DE) | 2008-07-02 | — | — | EP | claimed |
| US-7273058-B2 | Dividing hair into individual strands and winding on curlers; prior to application on hair, mixing shaping component with dye component having keratin-reducing agent and 4,5-diaminopyrazole and/or aminophenol derivative(s); fixing, rinsing | WELLA AG (DE) | 2007-09-25 | — | — | US | claimed |
| US-7241892-B1 | Hemisynthetic method and new compounds | PHARMA MAR, S.A. (ES) | 2007-07-10 | — | — | US | claimed |
| US-20060096042-A1 | Process to color and permanently restructure hair | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-05-11 | — | — | US | claimed |
| WO-2002049993-A2 | HIGH AFFINITY SMALL MOLECULE C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2002-06-27 | — | — | WO | claimed |
| WO-2002006207-A2 | NOVEL COUPLING COMPONENTS FOR OXIDATION COLOURING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-01-24 | — | — | WO | claimed |
| EP-1028694-A1 | APPLICATION OF INDANONES FOR DYING FIBERS CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-08-23 | — | — | EP | claimed |
| WO-2000038634-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-07-06 | — | — | WO | claimed |
| EP-0880352-B1 | STABILIZATION OF NALOXONE HYDROCHLORIDE | GOEDECKE AG (DE) | 1999-11-17 | — | — | EP | claimed |
| WO-1999018914-A2 | APPLICATION OF INDANONES FOR DYING FIBERS CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-04-22 | — | — | WO | claimed |
| US-5084067-A | Indoaniline dyes for hair dyes | L'OREAL (FR) | 1992-01-28 | — | — | US | claimed |
| EP-0400330-A1 | Oxidation hair dyes | Wella Aktiengesellschaft (DE) | 1990-12-05 | — | — | EP | claimed |
| EP-0287828-A1 | Intermediates and their preparation | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1988-10-26 | — | — | EP | claimed |
| EP-0095454-A2 | Nuclens-substituted pyrogallol derivatives | Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) | 1983-11-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10224485-B2 | Process for preparing a crystalline organic semiconductor material | STOM, SPOP, TTR | ABCG2 1774/4885AOC3 2038/4885KDM4C 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.