Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
| ▸ | ITGAL | P20701 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 2/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535019 | 0.91 | KDM4E (0.42) | ITGB2ICAM1ITGALKDM4EMTNR1A | |
| SCHEMBL9534791 | 0.91 | KDM4E (0.42) | ITGB2ICAM1ITGALKDM4EMTNR1A | |
| SCHEMBL11188752 | 0.86 | SMN1; SMN2 (0.57) | ITGB2ICAM1ITGALKDM4EMTNR1A | |
| SCHEMBL11194835 | 0.86 | SMN1; SMN2 (0.57) | ITGB2ICAM1ITGALKDM4EMTNR1A | |
| SCHEMBL118556 | 0.82 | ABCG2 (0.50) | KDM4ELMNAGAACHRNB4CHRNA3 | |
| Ethoxycarbonyl Group SCHEMBL27398991 | 0.79 | MTNR1A (0.42) | KDM4EMTNR1ACTNNB1WNT3ADAO | |
| SCHEMBL3072409 | 0.76 | ITGB2 (0.55) | ITGB2ICAM1ITGALKDM4EMTNR1A | |
| SCHEMBL10525725 | 0.75 | ITGB2 (0.60) | ITGB2ICAM1ITGALKDM4EMTNR1A | |
| SCHEMBL2938216 | 0.75 | CHEK2 (0.40) | ITGB2ICAM1ITGALKDM4EMTNR1A | |
| SCHEMBL3077219 | 0.75 | DRD2 (0.53) | ITGB2ICAM1ITGALKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044418-A1 | HIGH TEMPERATURE STABILIZER FOR POLYMER-BASED TREATMENT FLUIDS | SCHLUMBERGER TECHNOLOGY CORP (US) | 2017-02-16 | — | — | US | claimed |
| EP-3096735-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | Combe International Ltd. (US) | 2016-11-30 | — | — | EP | claimed |
| WO-2016160363-A1 | METHOD FOR TREATING A SUBTERRANEAN FORMATION | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2016-10-06 | — | — | WO | claimed |
| US-20160289544-A1 | METHOD FOR TREATING A SUBTERRANEAN FORMATION | SCHLUMBERGER TECHNOLOGY CORPORATION | 2016-10-06 | — | — | US | claimed |
| CN-105916482-A | Gradual hair color compositions and methods of use thereof | 酷姆国际公司 | 2016-08-31 | — | — | CN | claimed |
| WO-2015171857-A1 | HIGH TEMPERATURE STABILIZER FOR POLYMER-BASED TREATMENT FLUIDS | SCHLUMBERGER CANADA LIMITED (CA) | 2015-11-12 | — | — | WO | claimed |
| WO-2015112789-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | COMBE INTERNATIONAL LTD. (US) | 2015-07-30 | — | — | WO | claimed |
| EP-1865914-B1 | IMPROVED OXIDATIVE HAIR DYES | BOOTS CO PLC (GB) | 2012-08-15 | — | — | EP | claimed |
| EP-1865914-A1 | IMPROVED OXIDATIVE HAIR DYES AND RELATED TOPICAL COMPOSITIONS | The Boots Company PLC (GB) | 2007-12-19 | — | — | EP | claimed |
| WO-2006106366-A1 | IMPROVED OXIDATIVE HAIR DYES AND RELATED TOPICAL COMPOSITIONS | THE BOOTS COMPANY PLC (GB) | 2006-10-12 | — | — | WO | claimed |
| US-20030140428-A1 | Gradual permanent coloring of hair using dye intermediates in a shampoo base | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-07-31 | — | — | US | claimed |
| US-20030074748-A1 | Method and composition for the gradual permanent coloring of hair | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-04-24 | — | — | US | claimed |
| US-20030040639-A1 | Method for the preparation of substituted benzene derivatives | H. LUNDBECK A/S (DK) | 2003-02-27 | — | — | US | claimed |
| EP-1246819-A1 | A METHOD FOR THE PREPARATION OF SUBSTITUTED BENZENE DERIVATIVES | H. Lundbeck A/S (DK) | 2002-10-09 | — | — | EP | claimed |
| WO-2001049681-A1 | A METHOD FOR THE PREPARATION OF SUBSTITUTED BENZENE DERIVATIVES | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | claimed |
| US-6074438-A | AN OXIDATIVE HAIR DYE MIXTURE COMPRISING PRIMARY INTERMEDIATE AND A COUPLER FORMING AN OXIDATIVE HAIR DYE IN THE PRESENCE OF AN OXIDIZING AGENT | BRISTOL-MYERS SQUIBB CO. (US) | 2000-06-13 | — | — | US | claimed |
| US-5540738-A | SIMULTANEOUSLY APPLYING IODIDE IONS, AN OXIDANT AND AN EFFECTIVE CONCENTRATION OF AN OXIDATION DYE TO PRODUCE INTENSE COLORS IN ALKALINE SOLUTION | CHAN ALEXANDER C (US) | 1996-07-30 | — | — | US | claimed |
| EP-0545257-B1 | Oxidative hair coloring compositions and process for dyeing human keratinous fibers | BRISTOL MYERS SQUIBB CO (US) | 1996-05-29 | — | — | EP | claimed |
| EP-0545257-A2 | Oxidative hair coloring compositions and process for dyeing human keratinous fibers | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-06-09 | — | — | EP | claimed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040639-A1 | Method for the preparation of substituted benzene derivatives | SCLY, CBR3, TST | ITGB2 3912/4885ICAM1 3711/4885ITGAL 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.