Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850654 | 0.76 | NQO1 (0.55) | KMT2AMEN1L3MBTL1NQO1PKM | |
| SCHEMBL18788969 | 0.73 | KDM4E (0.54) | KMT2AL3MBTL1NQO1RAB9APKM | |
| SCHEMBL7819859 | 0.71 | CALM1 (0.48) | CYP2C19L3MBTL1NQO1ALDH1A1KDM4E | |
| SCHEMBL9193035 | 0.71 | CALM1 (0.48) | NQO1ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL8100218 | 0.71 | CALM1 (0.55) | NQO1IDH1LMNA | |
| SCHEMBL31329416 | 0.71 | CTRC (0.42) | KMT2AMEN1L3MBTL1NQO1PKM | |
| SCHEMBL1919725 | 0.71 | TYMP (0.49) | KMT2AMEN1NQO1ALDH1A1KDM4E | |
| SCHEMBL11857671 | 0.70 | MAPT (0.53) | KMT2AMEN1L3MBTL1RAB9APKM | |
| SCHEMBL11851803 | 0.69 | ALDH1A1 (0.50) | KMT2AMEN1L3MBTL1USP2PKM | |
| SCHEMBL5663531 | 0.69 | TNKS2 (0.49) | CYP2C19NQO1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972888-A | Process for the preparation of 1-hydroxy-pyridones | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |