Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11857285 | 0.99 | HRH4 (0.62) | HRH4PIK3CAHTR3AHTR2AKDM4E | |
| SCHEMBL11860847 | 0.92 | PIK3CA (0.59) | HRH4PIK3CAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11862975 | 0.86 | PIK3CA (0.54) | HRH4PIK3CAKDM4EALDH1A1HTT | |
| SCHEMBL11849800 | 0.85 | PIK3CA (0.53) | HRH4PIK3CAHTR3AHTR2AKDM4E | |
| SCHEMBL11853830 | 0.85 | HRH4 (0.63) | HRH4PIK3CAKDM4EALDH1A1 | |
| SCHEMBL11866288 | 0.85 | PIK3CA (0.53) | HRH4PIK3CAHTR3AHTR2AKDM4E | |
| SCHEMBL11856867 | 0.85 | PIK3CA (0.51) | HRH4PIK3CAGBA1 | |
| SCHEMBL11852798 | 0.85 | LMNA (0.51) | HRH4PIK3CAKDM4EALDH1A1GBA1 | |
| SCHEMBL11859522 | 0.84 | PIK3CA (0.50) | HRH4PIK3CAKDM4EALDH1A1GBA1 | |
| Hydrochloric Acid SCHEMBL11857828 | 0.84 | HRH4 (0.62) | HRH4PIK3CAKDM4EALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | disclosed |