Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 5/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860847 | 0.87 | PIK3CA (0.59) | PIK3CAHRH4MTORPIK3R1PIK3CD | |
| SCHEMBL11857231 | 0.86 | HTR3E (0.53) | PIK3CAHRH4SMOMTORPIK3R1 | |
| SCHEMBL11857710 | 0.86 | HTR3E (0.53) | PIK3CAHRH4SMOMTORPIK3R1 | |
| SCHEMBL11851990 | 0.86 | SLC6A7 (0.52) | PIK3CAMTORPIK3R1GBA1 | |
| SCHEMBL11856434 | 0.85 | HRH4 (0.63) | PIK3CAHRH4GBA1 | |
| Hydrochloric Acid SCHEMBL11857285 | 0.84 | HRH4 (0.62) | PIK3CAHRH4 | |
| SCHEMBL11852798 | 0.82 | LMNA (0.51) | PIK3CAHRH4SMOMTORPIK3R1 | |
| SCHEMBL11859522 | 0.82 | PIK3CA (0.50) | PIK3CAHRH4MTORPIK3R1PIK3CD | |
| Hydrochloric Acid SCHEMBL11862975 | 0.81 | PIK3CA (0.54) | PIK3CAHRH4MTORPIK3CDPIK3CG | |
| SCHEMBL11849800 | 0.80 | PIK3CA (0.53) | PIK3CAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | disclosed |