Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 15/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.44 |
| ▸ | MTOR | P42345 | 8/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11862975 | 0.93 | PIK3CA (0.54) | PIK3CAHRH4PIK3CDPIK3CGMTOR | |
| SCHEMBL11866288 | 0.92 | PIK3CA (0.53) | PIK3CAHRH4HPGDKDM4EALDH1A1 | |
| SCHEMBL11856434 | 0.92 | HRH4 (0.63) | PIK3CAHRH4KDM4EALDH1A1 | |
| SCHEMBL11849800 | 0.92 | PIK3CA (0.53) | PIK3CAHRH4HPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11857285 | 0.91 | HRH4 (0.62) | PIK3CAHRH4KDM4EALDH1A1 | |
| SCHEMBL11859522 | 0.89 | PIK3CA (0.50) | PIK3CAHRH4PIK3CDPIK3CGMTOR | |
| SCHEMBL11852798 | 0.87 | LMNA (0.51) | PIK3CAHRH4PIK3CDPIK3CGMTOR | |
| SCHEMBL11856867 | 0.87 | PIK3CA (0.51) | PIK3CAHRH4PIK3CDPIK3CGMTOR | |
| SCHEMBL11851990 | 0.84 | SLC6A7 (0.52) | PIK3CAMTORTSHRL3MBTL1PIK3R1 | |
| SCHEMBL11848455 | 0.84 | PIK3CA (0.58) | PIK3CAHRH4PIK3CDPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | disclosed |