SCHEMBL11856441

SCHEMBL11856441

CCOC(=O)Cc1ccc(C2=CCCCC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4Z1 Q86W10 1/20 0.45
ACMSD Q8TDX5 1/20 0.43
MAPT P10636 2/20 0.43
HDAC1 Q13547 2/20 0.42
HDAC2 Q92769 2/20 0.42
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LIPE Q05469 1/20 0.41
JAK2 O60674 1/20 0.40
JAK3 P52333 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30730343 0.87 SMN1; SMN2 (0.45) CYP4Z1ACMSDHDAC1HDAC2SMN1; SMN2
SCHEMBL32661133 0.83 PSMB5 (0.38) CYP4Z1ACMSDHDAC1HDAC2SMN1; SMN2
SCHEMBL32661309 0.82 PSMB5 (0.38) CYP4Z1ACMSDHDAC1HDAC2SMN1; SMN2
SCHEMBL32661412 0.82 PSMB5 (0.38) CYP4Z1ACMSDHDAC1HDAC2SMN1; SMN2
SCHEMBL11833452 0.81 HPGD (0.40) ACMSDMAPTHDAC1HDAC2LMNA
SCHEMBL6068636 0.81 CA12 (0.51) ACMSDMAPTLMNASMN1; SMN2JAK2
SCHEMBL68930 0.81 CYP4Z1 (0.57) CYP4Z1MAPTLMNASMN1; SMN2LIPE
SCHEMBL30730411 0.79 LIPE (0.46) CYP4Z1MAPTLMNASMN1; SMN2LIPE
SCHEMBL68851 0.79 CYP4Z1 (0.62) CYP4Z1MAPTLMNASMN1; SMN2LIPE
SCHEMBL19440710 0.78 CYP4Z1 (0.41) CYP4Z1MAPTLMNASMN1; SMN2LIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4562015-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
WO-2024026481-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
US-3944589-A α-Cycloalkenylphenyl-fatty acid nitriles CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed