SCHEMBL68930

SCHEMBL68930

CCOC(=O)Cc1ccc(-c2ccc(CC(=O)OCC)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4Z1 Q86W10 1/20 0.57
MAPT P10636 2/20 0.54
LMNA P02545 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
ALDH1A1 P00352 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
THRB P10828 1/20 0.49
KDM4E B2RXH2 1/20 0.48
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
NPC1 O15118 1/20 0.48
PKM P14618 1/20 0.48
NFKB1 P19838 1/20 0.48
RAB9A P51151 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
PPID Q08752 1/20 0.48
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12126600 0.94 CYP4Z1 (0.53) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL68851 0.94 CYP4Z1 (0.62) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL11363373 0.93 SENP1 (0.53) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL3227634 0.93 GAA (0.58) CYP4Z1LMNASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL12987888 0.91 CYP1A2 (0.51) CYP4Z1MAPTLMNASMN1; SMN2ALDH1A1
Hydrochloric Acid SCHEMBL7390203 0.91 L3MBTL1 (0.56) MAPTLMNASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL8069266 0.91 CYP4Z1 (0.50) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL11847298 0.91 MAPT (0.51) CYP4Z1MAPTLMNASMN1; SMN2CYP4F2
SCHEMBL9347360 0.89 KMT2A (0.59) MAPTALDH1A1L3MBTL1HSD17B10GAA
SCHEMBL15723417 0.88 ALDH1A1 (0.57) CYP4Z1MAPTCYP4F2CYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CYP4Z1 799/4885MAPT 1923/4885LMNA 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.