SCHEMBL11857028

SCHEMBL11857028

O=C(O)C(c1ccc(Cl)cc1Cl)C1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 14/20 0.49
CNR2 P34972 13/20 0.49
NPSR1 Q6W5P4 1/20 0.49
RAB9A P51151 2/20 0.45
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11855303 0.98 CNR1 (0.48) CNR1CNR2NPSR1RAB9ASLC6A3
SCHEMBL10006283 0.84 CNR1 (0.49) CNR1CNR2
SCHEMBL17847157 0.84 RAB9A (0.43) CNR1CNR2NPSR1RAB9ASLC6A3
SCHEMBL11854426 0.83 SLC6A3 (0.62) CNR1CNR2NPSR1RAB9ASLC6A3
SCHEMBL9942278 0.82 NPSR1 (0.44) CNR1CNR2NPSR1RAB9ASLC6A3
SCHEMBL2788659 0.81 TAS1R3 (0.45) CNR1RAB9ASLC6A3
SCHEMBL11855296 0.81 SLC6A3 (0.61) CNR1CNR2NPSR1RAB9ASLC6A3
SCHEMBL10006401 0.79 SLC6A3 (0.49) CNR1CNR2NPSR1RAB9ASLC6A3
SCHEMBL3953759 0.76 NPC1 (0.48) CNR1CNR2RAB9ASLC6A3
SCHEMBL3953705 0.76 NPC1 (0.48) CNR1CNR2RAB9ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3991201-A 1-(β-Aryl-β-R-ethyl)imidazoles as antimicrobial agents JANSSEN PHARMACEUTICA N.V. (BE) 1976-11-09 US disclosed