Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860205 | 0.88 | MALT1 (0.66) | MALT1POLBKMT2APPP1CASMN1; SMN2 | |
| SCHEMBL11866066 | 0.84 | SMN1; SMN2 (0.56) | POLBMAPTKMT2ATDP1PPP1CA | |
| SCHEMBL11864162 | 0.82 | MALT1 (0.44) | MALT1MAPTKMT2ATDP1PPP1CA | |
| SCHEMBL30482104 | 0.80 | MALT1 (0.50) | MALT1POLBKMT2APPP1CATP53 | |
| SCHEMBL5109068 | 0.80 | MALT1 (0.50) | MALT1POLBKMT2APPP1CATP53 | |
| SCHEMBL11862128 | 0.79 | RPA1 (0.51) | MALT1POLBMAPTKMT2ATDP1 | |
| SCHEMBL2320824 | 0.72 | ALDH1A1 (0.59) | POLBMAPTKMT2ATDP1PPP1CA | |
| SCHEMBL11860723 | 0.71 | POLB (0.61) | MALT1POLBKMT2APPP1CASMN1; SMN2 | |
| SCHEMBL11863727 | 0.71 | MALT1 (0.58) | MALT1POLBKMT2APPP1CASMN1; SMN2 | |
| SCHEMBL15682943 | 0.71 | MAPT (0.50) | POLBMAPTKMT2ATDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953467-A | ANALYGESICS, ANTIINFLAMMATORY AGENTS | MARUKO SEIYAKU CO., LTD. (JA) | 1976-04-27 | — | — | US | claimed |
| US-3953467-A | ANALYGESICS, ANTIINFLAMMATORY AGENTS | MARUKO SEIYAKU CO., LTD. (JA) | 1976-04-27 | — | — | US | disclosed |