Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RPA1 | P27694 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MARS1 | P56192 | 1/20 | 0.53 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866066 | 0.87 | SMN1; SMN2 (0.56) | POLBRPA1SMN1; SMN2PPP1CAMEN1 | |
| SCHEMBL2320824 | 0.86 | ALDH1A1 (0.59) | POLBRPA1PPP1CAL3MBTL1KMT2A | |
| SCHEMBL11860205 | 0.85 | MALT1 (0.66) | POLBRPA1SMN1; SMN2PPP1CAMEN1 | |
| SCHEMBL2865749 | 0.80 | SMN1; SMN2 (0.66) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL2318841 | 0.78 | RPA1 (0.68) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL2320255 | 0.77 | MARS1 (0.49) | RPA1PPP1CAL3MBTL1MEN1KMT2A | |
| SCHEMBL2322024 | 0.76 | THRB (0.50) | POLBRPA1PPP1CAMEN1KMT2A | |
| SCHEMBL4488017 | 0.76 | RPA1 (1.00) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 | |
| SCHEMBL15682943 | 0.76 | MAPT (0.50) | POLBRPA1MEN1KMT2A | |
| SCHEMBL4509457 | 0.75 | RPA1 (0.59) | RPA1SMN1; SMN2PPP1CAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953467-A | ANALYGESICS, ANTIINFLAMMATORY AGENTS | MARUKO SEIYAKU CO., LTD. (JA) | 1976-04-27 | — | — | US | disclosed |