Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763413 | 0.89 | ADH1B (0.46) | TDP1TAAR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7677679 | 0.79 | FFAR2 (0.46) | ALDH1A1SMN1; SMN2HTTADRB2TYR | |
| SCHEMBL5561037 | 0.79 | SMN1; SMN2 (0.46) | LMNACYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL29062520 | 0.79 | HTT (0.46) | MAPKAPK2CYP2C9LMNACYP3A4CYP2D6 | |
| SCHEMBL5565853 | 0.79 | SMN1; SMN2 (0.46) | LMNACYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL7677677 | 0.79 | FFAR2 (0.46) | ALDH1A1SMN1; SMN2HTTADRB2TYR | |
| SCHEMBL14186856 | 0.79 | HTT (0.46) | MAPKAPK2CYP2C9LMNACYP3A4CYP2D6 | |
| SCHEMBL1911630 | 0.79 | HTT (0.46) | MAPKAPK2CYP2C9LMNACYP3A4CYP2D6 | |
| SCHEMBL20811278 | 0.79 | FFAR2 (0.46) | ALDH1A1SMN1; SMN2HTTADRB2TYR | |
| SCHEMBL5566179 | 0.79 | SMN1; SMN2 (0.46) | LMNACYP1A2CYP2C19ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954709-A | Phenylethyl group containing resins for the synthesis of peptides | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 1976-05-04 | — | — | US | claimed |