Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 4/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677677 | 1.00 | FFAR2 (0.46) | FFAR2ADRB2GAAHPGDSMN1; SMN2 | |
| SCHEMBL20811278 | 1.00 | FFAR2 (0.46) | FFAR2ADRB2GAAHPGDSMN1; SMN2 | |
| SCHEMBL8763413 | 0.89 | ADH1B (0.46) | GAASMN1; SMN2TYRALDH1A1HTT | |
| SCHEMBL5565853 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL11857789 | 0.79 | ESR1 (0.48) | ADRB2SMN1; SMN2TYRALDH1A1HTT | |
| SCHEMBL29062520 | 0.79 | HTT (0.46) | ADRB2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL1911630 | 0.79 | HTT (0.46) | ADRB2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL14186856 | 0.79 | HTT (0.46) | ADRB2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL5561037 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL5566179 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500986-B1 | RACEMIZATION OF OPTICALLY ACTIVE AMIDES; CONVERSION TO AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | claimed |
| EP-0757981-B1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 2000-02-16 | — | — | EP | claimed |
| EP-0757981-A1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 1997-02-12 | — | — | EP | claimed |
| US-6500986-B1 | RACEMIZATION OF OPTICALLY ACTIVE AMIDES; CONVERSION TO AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| US-6093851-A | N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0757981-B1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 2000-02-16 | — | — | EP | disclosed |
| EP-0735018-B1 | N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL CO (JP) | 1999-07-21 | — | — | EP | disclosed |
| US-5739401-A | N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0757981-A1 | Process for the preparation of racemic amino derivatives | BAYER AG (DE) | 1997-02-12 | — | — | EP | disclosed |
| EP-0735018-A1 | N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |