Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | PARG | Q86W56 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 12/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858997 | 0.85 | GRIN1 (0.44) | GRIN1GRIN2BADORA1MERTK | |
| SCHEMBL11166292 | 0.83 | PTGS2 (0.47) | PARGCNR2KCNH2PTGS2 | |
| SCHEMBL11636366 | 0.83 | GRIN1 (0.44) | GRIN1GRIN2B | |
| SCHEMBL11156465 | 0.83 | GRIN1 (0.42) | GRIN1GRIN2B | |
| SCHEMBL11865450 | 0.83 | GRIN1 (0.42) | GRIN1GRIN2BADORA1MERTK | |
| SCHEMBL11865844 | 0.83 | PTGS2 (0.42) | SCDPARGPTGS2 | |
| SCHEMBL11862223 | 0.82 | GRIN1 (0.45) | GRIN1GRIN2BADORA1MERTK | |
| SCHEMBL11866771 | 0.82 | GRIN1 (0.42) | GRIN1GRIN2BADORA1 | |
| SCHEMBL11863918 | 0.82 | GRIN1 (0.46) | GRIN1GRIN2BADORA1MERTK | |
| SCHEMBL11870097 | 0.80 | PARG (0.38) | PARGCNR2KCNH2PTGS2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | claimed |
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |