Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684907 | 0.87 | SIGMAR1 (0.70) | SIGMAR1OPRD1OPRM1OPRK1ADRA2A | |
| SCHEMBL12175587 | 0.84 | PRCP (0.65) | SIGMAR1 | |
| SCHEMBL11858736 | 0.83 | OPRD1 (0.54) | SIGMAR1OPRD1OPRM1OPRK1ADRA2A | |
| SCHEMBL11863710 | 0.82 | SIGMAR1 (0.60) | SIGMAR1OPRD1OPRM1OPRK1ADRA2A | |
| SCHEMBL11682895 | 0.81 | KCNH2 (0.57) | SIGMAR1OPRD1OPRM1OPRK1ADRA2A | |
| SCHEMBL12175582 | 0.81 | PRCP (0.59) | SIGMAR1 | |
| SCHEMBL11843820 | 0.81 | OPRD1 (0.47) | SIGMAR1OPRD1OPRM1OPRK1ADRA2A | |
| SCHEMBL11870243 | 0.81 | OPRD1 (0.52) | SIGMAR1OPRD1OPRM1OPRK1ADRA2A | |
| SCHEMBL12175586 | 0.81 | PRCP (0.66) | — | |
| SCHEMBL15894617 | 0.81 | PRCP (0.61) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |