Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.56 |
| ▸ | EBP | Q15125 | 2/20 | 0.56 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684907 | 0.92 | SIGMAR1 (0.70) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A | |
| SCHEMBL11859408 | 0.84 | OPRD1 (0.47) | SIGMAR1OPRM1OPRK1OPRD1 | |
| SCHEMBL11778403 | 0.83 | OPRD1 (0.47) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A | |
| SCHEMBL11859292 | 0.82 | SIGMAR1 (0.60) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A | |
| SCHEMBL11849041 | 0.82 | OPRD1 (0.46) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A | |
| SCHEMBL11858736 | 0.81 | OPRD1 (0.54) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A | |
| SCHEMBL3918703 | 0.81 | SIGMAR1 (0.86) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A | |
| SCHEMBL11851978 | 0.79 | KCNH2 (0.52) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A | |
| SCHEMBL11870243 | 0.79 | OPRD1 (0.52) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A | |
| SCHEMBL11781143 | 0.78 | SIGMAR1 (0.51) | SIGMAR1OPRM1OPRK1OPRD1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |