Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.58 |
| ▸ | NOS2 | P35228 | 6/20 | 0.51 |
| ▸ | NOS3 | P29474 | 3/20 | 0.51 |
| ▸ | NOS1 | P29475 | 3/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15936977 | 0.98 | LCK (0.56) | LCKNOS2NOS3NOS1LNPEP | |
| SCHEMBL11849660 | 0.93 | LCK (0.65) | LCKLNPEPERAP2ERAP1OPRK1 | |
| Hydrochloric Acid SCHEMBL11684930 | 0.92 | LCK (0.64) | LCKLNPEPERAP2ERAP1OPRK1 | |
| SCHEMBL11850273 | 0.90 | LCK (0.59) | LCKLNPEPERAP2OPRK1HSD17B10 | |
| SCHEMBL11859518 | 0.90 | LCK (0.59) | LCKLNPEPERAP2OPRK1HSD17B10 | |
| SCHEMBL30032159 | 0.86 | OPRK1 (0.64) | NOS2NOS3NOS1OPRK1HSD17B10 | |
| SCHEMBL11854644 | 0.84 | LCK (0.60) | LCKERAP2ERAP1HSD17B10KDM4E | |
| SCHEMBL11857999 | 0.84 | LCK (0.54) | LCKERAP2ERAP1HSD17B10KDM4E | |
| SCHEMBL11850734 | 0.83 | LCK (0.53) | LCKLNPEPERAP2ERAP1OPRK1 | |
| SCHEMBL8093509 | 0.82 | LCK (0.53) | LCKLNPEPERAP2ERAP1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190201349-A1 | CAPSULES AND PARTICLES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2019-07-04 | — | — | US | disclosed |
| US-20180079912-A1 | ANTIFOULING MATERIALS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2018-03-22 | — | — | US | disclosed |
| US-9631100-B2 | Antifouling materials | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2017-04-25 | — | — | US | disclosed |
| US-20150368480-A1 | ANTIFOULING MATERIALS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079912-A1 | ANTIFOULING MATERIALS | PFAS, FLNB, FLNA | LCK 3732/4885NOS2 617/4885NOS3 486/4885 |
| US-20190201349-A1 | CAPSULES AND PARTICLES AND USES THEREOF | ALG1, LPO, FUT5 | LCK 4600/4885NOS2 1966/4885NOS3 2160/4885 |
| US-20150368480-A1 | ANTIFOULING MATERIALS | PFAS, FLNB, FLNA | LCK 3732/4885NOS2 617/4885NOS3 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.