Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2851617 | 0.79 | NPC1 (0.59) | RAB9ANPC1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL29887199 | 0.79 | NPC1 (0.59) | RAB9ANPC1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL11777157 | 0.72 | LMNA (0.32) | LMNA | |
| SCHEMBL3652642 | 0.69 | NPC1 (1.00) | RAB9ANPC1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL12518213 | 0.68 | MAPT (0.65) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL20733792 | 0.67 | RAB9A (0.62) | RAB9ANPC1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL17104884 | 0.66 | RAB9A (0.60) | RAB9ANPC1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL3445210 | 0.66 | SMN1; SMN2 (0.81) | RAB9ANPC1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL23143288 | 0.65 | SMN1; SMN2 (0.56) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24729180 | 0.64 | RAB9A (0.45) | RAB9ANPC1MAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962240-A | PROCESS FOR THE PREPARATION OF FURO(3,4-E)-AS-TRIAZINES | SANDOZ, INC. (US) | 1976-06-08 | — | — | US | disclosed |