Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ACHE | P22303 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL2063451 | 0.88 | ACHE (0.69) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL8845007 | 0.88 | ACHE (0.69) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL8334068 | 0.87 | TSHR (0.52) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL28269304 | 0.86 | ACHE (0.65) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL8845046 | 0.85 | TSHR (0.52) | LMNAACHETSHRALOX12TP53 | |
| Toluene SCHEMBL5595092 | 0.85 | ACHE (0.73) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL11448382 | 0.85 | ACHE (0.73) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL330032 | 0.85 | ACHE (0.73) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL991792 | 0.85 | ACHE (0.73) | LMNAACHETSHRALOX12POLB | |
| Toluene SCHEMBL11219192 | 0.84 | TSHR (0.55) | LMNAACHETSHRALOX12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623806-A | Polybenzimidazole with side ammonium groups, anion exchange membrane thereof and preparation method thereof | 大连理工大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-104511310-A | Mesoporous carbon supported N-heterocyclic carbene-palladium catalyst as well as preparation and application thereof | EAST CHINA INST TECHNOLOGY | 2015-04-15 | — | — | CN | disclosed |
| US-3933752-A | COPOLYMERIZATION USING ARENE-METAL TRICARBONYL FRIEDEL-CRAFTS CATALYSTS | THE UNIVERSITY OF AKRON (US) | 1976-01-20 | — | — | US | disclosed |