Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL5595092 | 1.00 | ACHE (0.73) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL11448382 | 1.00 | ACHE (0.73) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL28673606 | 0.94 | ACHE (0.65) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL5671767 | 0.94 | ACHE (0.65) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL8213424 | 0.91 | ACHE (0.61) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL8979310 | 0.91 | ACHE (0.61) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL2063451 | 0.90 | ACHE (0.69) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL8845007 | 0.90 | ACHE (0.69) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL9410087 | 0.89 | LMNA (0.58) | ACHELMNATSHRALOX12POLB | |
| Toluene SCHEMBL7463284 | 0.87 | LMNA (0.55) | ACHELMNATSHRALOX12POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1085 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981678-A | Method for synthesizing reactive carbohydrates comprising antigen precursors for conjugation to a carrier material | 科兰克斯资本 | 2023-10-31 | — | — | CN | claimed |
| CN-116514669-A | Synthesis method of 2-chloro-5-phenoxyaniline | 上海灵瑞医药有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-110569942-B | Preparation method of multiple anti-counterfeiting fluorescent two-dimensional code device | 浙江工业大学 | 2023-05-23 | — | — | CN | claimed |
| US-20230125064-A2 | CRYSTAL FORM OF PHOSPHODIESTERASE INHIBITOR,PREPARATION METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2023-04-20 | — | — | US | claimed |
| CN-114058038-B | Preparation method of hydrogel material for rapid hemostasis | 武汉大学中南医院 | 2023-03-28 | — | — | CN | claimed |
| US-20220194934-A1 | CRYSTAL FORM OF PHOSPHODIESTERASE INHIBITOR,PREPARATION METHOD THEREFOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2022-06-23 | — | — | US | claimed |
| CN-114058038-A | Preparation method of hydrogel material for rapid hemostasis | 武汉大学中南医院 | 2022-02-18 | — | — | CN | claimed |
| EP-3939978-A1 | CRYSTAL FORM OF PHOSPHODIESTERASE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Transthera Sciences (Nanjing), Inc. (CN) | 2022-01-19 | — | — | EP | claimed |
| CN-113754909-A | Graphene-natural rubber composite toughening modified polylactic acid film and preparation method thereof | 陈运恒 | 2021-12-07 | — | — | CN | claimed |
| CN-111689958-B | Crystal forms of phosphodiesterase inhibitors, preparation method and uses thereof | 南京药捷安康生物科技有限公司 | 2021-11-19 | — | — | CN | claimed |
| US-20040014998-A1 | Process for the preparation of baccatin III derivatives | INDENA S.P.A. (IT) | 2004-01-22 | — | — | US | claimed |
| US-6670472-B2 | Reacting 10-methoxyiminostilbene with cyanic acid (HOCN) in a solvent therefor in the presence of a mild acidic reagent to produce 10-methoxycarbamazepine | MAX INDIA LIMITED (IN) | 2003-12-30 | — | — | US | claimed |
| US-20030235696-A1 | Polysiloxane(amide-ureide) anti-ice coating | THE BOEING COMPANY | 2003-12-25 | — | — | US | claimed |
| EP-1347984-A2 | A PROCESS FOR THE PREPARATION OF TAXAN DERIVATIVES | INDENA S.p.A. (IT) | 2003-10-01 | — | — | EP | claimed |
| US-20030105076-A1 | Process for the preparation of 10-methoxycarbamazepine | JUBILANT ORGANOSYS LTD (IN) | 2003-06-05 | — | — | US | claimed |
| EP-1307436-A1 | PROCESS FOR THE PREPARATION OF BACCATIN III DERIVATIVES | INDENA S.p.A. (IT) | 2003-05-07 | — | — | EP | claimed |
| WO-2002044161-A2 | A PROCESS FOR THE PREPARATION OF TAXAN DERIVATIVES | INDENA S.P.A. (IT) | 2002-06-06 | — | — | WO | claimed |
| WO-2002012215-A1 | PROCESS FOR THE PREPARATION OF BACCATIN III DERIVATIVES | INDENA S.P.A. (IT) | 2002-02-14 | — | — | WO | claimed |
| EP-0107080-A1 | Decolorizing polymers of epihalohydrin | The B.F. GOODRICH Company (US) | 1984-05-02 | — | — | EP | claimed |
| US-4144254-A | ADSORPTION OF IMPURITIES ON BASIC ALUMINA, CRYSTALLIZATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1979-03-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105076-A1 | Process for the preparation of 10-methoxycarbamazepine | PARK7, BCHE, DBH | ACHE 14/4885LMNA 1249/4885TSHR 4726/4885 |
| US-20040014998-A1 | Process for the preparation of baccatin III derivatives | BBC3, CYP8B1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ACHE 3713/4885LMNA 221/4885TSHR 4877/4885 |
| US-20220194934-A1 | CRYSTAL FORM OF PHOSPHODIESTERASE INHIBITOR,PREPARATION METHOD THEREFOR AND USE THEREOF | PDE3A, PDE5A, PDE3B | ACHE 72/4885LMNA 1620/4885TSHR 2887/4885 |
| US-20230125064-A2 | CRYSTAL FORM OF PHOSPHODIESTERASE INHIBITOR,PREPARATION METHOD THEREFOR AND USE THEREOF | PDE3A, PDE5A, PDE3B | ACHE 72/4885LMNA 1620/4885TSHR 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.