Toluene

Toluene

SCHEMBL8845007

CCCl.Cc1ccccc1

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.69
LMNA P02545 3/20 0.69
TSHR P16473 2/20 0.69
ALOX12 P18054 1/20 0.69
POLB P06746 2/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 2/20 0.42
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HTT P42858 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CYP2C19 P33261 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
NPSR1 Q6W5P4 1/20 0.37
PSIP1 O75475 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL11448382 0.90 ACHE (0.73) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL5595092 0.90 ACHE (0.73) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL330032 0.90 ACHE (0.73) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL11862000 0.88 LMNA (0.61) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL2063451 0.88 ACHE (0.69) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL28260985 0.88 ACHE (0.69) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL28126829 0.88 ACHE (0.69) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL27708439 0.88 ACHE (0.69) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL6697996 0.87 ACHE (0.79) ACHELMNATSHRALOX12POLB
Toluene SCHEMBL9410087 0.86 LMNA (0.58) ACHELMNATSHRALOX12POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292597-B Method for preparing triethyl phosphate compound by recovering sodium diethylphosphate and ethyl chloride 浙江宏达化学制品有限公司 2023-03-24 CN disclosed
CN-113292597-A Preparation method of phosphate compound 浙江宏达化学制品有限公司 2021-08-24 CN disclosed
CN-106132926-B Method for producing tribenzyloxycarbonyl arginine 株式会社钟化 2019-05-21 CN disclosed
CN-106132926-A Method for producing tribenzyloxycarbonyl arginine 株式会社钟化 2016-11-16 CN disclosed
US-5668232-A Process for the production of polyisoolefins BAYER AG (DE) 1997-09-16 US disclosed