Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862946 | 0.75 | NQO1 (0.46) | MAOBNQO1PRKDCKDM4EMAPT | |
| SCHEMBL21591443 | 0.72 | PTPN1 (0.56) | PTPN1POLBMEN1KMT2AMAOA | |
| SCHEMBL11865039 | 0.71 | PTPN1 (0.54) | PTPN1POLBMEN1KMT2AMAOA | |
| SCHEMBL29951632 | 0.69 | PTPN1 (0.56) | PTPN1POLBMEN1KMT2AMAOA | |
| SCHEMBL1306154 | 0.69 | PTPN1 (0.56) | PTPN1POLBMEN1KMT2AMAOA | |
| SCHEMBL11252346 | 0.68 | PTPN1 (0.54) | PTPN1POLBMEN1KMT2AMAOA | |
| SCHEMBL11872015 | 0.68 | PTPN1 (1.00) | PTPN1POLBMEN1KMT2AMAOA | |
| SCHEMBL29950744 | 0.68 | PTPN1 (1.00) | PTPN1POLBMEN1KMT2AMAOA | |
| SCHEMBL29954142 | 0.67 | PTPN1 (0.54) | PTPN1POLBMEN1KMT2AMAOA | |
| SCHEMBL30307601 | 0.66 | PTPN1 (0.62) | PTPN1POLBMEN1KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959480-A | Polycyclic gamma-pyrone-3-carboxaldehyde derivatives | WARNER-LAMBERT COMPANY (US) | 1976-05-25 | — | — | US | disclosed |