Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11872015 | 1.00 | PTPN1 (1.00) | PTPN1POLBKMT2AMEN1MAOA | |
| SCHEMBL30017579 | 0.82 | PTPN1 (0.69) | PTPN1POLBKMT2AMEN1MAOA | |
| SCHEMBL31037935 | 0.77 | POLB (0.62) | PTPN1POLBKMT2AMEN1MAPT | |
| SCHEMBL28569270 | 0.77 | POLB (0.62) | PTPN1POLBKMT2AMEN1MAPT | |
| SCHEMBL30307601 | 0.75 | PTPN1 (0.62) | PTPN1POLBKMT2AMEN1MAOA | |
| SCHEMBL30307600 | 0.75 | PTPN1 (0.62) | PTPN1POLBKMT2AMEN1MAOA | |
| SCHEMBL21591567 | 0.75 | PTPN1 (0.60) | PTPN1POLBKMT2AMEN1MAOA | |
| SCHEMBL11869804 | 0.74 | POLB (0.59) | PTPN1POLBKMT2AMEN1MAOB | |
| SCHEMBL127924 | 0.74 | PTPN1 (1.00) | PTPN1POLBKMT2AMEN1MAOA | |
| SCHEMBL29952282 | 0.74 | PTPN1 (1.00) | PTPN1POLBKMT2AMEN1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |