Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862600 | 0.75 | PTPN1 (0.51) | NQO1MAOBKDM4EMAPTPRKDC | |
| SCHEMBL21591539 | 0.73 | SMN1; SMN2 (0.59) | NQO1MAOBMAPTALDH1A1HPGD | |
| SCHEMBL11873585 | 0.72 | MAOB (0.53) | MAOBKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL11616224 | 0.71 | MAOB (0.56) | MAOBCES1SMN1; SMN2ALOX15ALOX12 | |
| SCHEMBL11869804 | 0.70 | POLB (0.59) | MAOBKDM4EMAPTPRKDCALDH1A1 | |
| SCHEMBL11622080 | 0.68 | MAOB (0.56) | MAOBALOX15ALOX12 | |
| SCHEMBL28199787 | 0.65 | KIF11 (0.44) | NQO1KIF11GRIA1GRIA2GRIA3 | |
| SCHEMBL11618420 | 0.65 | ALDH1A1 (0.53) | MAOBKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL11618941 | 0.65 | MAOB (0.51) | MAOBKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11620092 | 0.64 | MAOB (0.46) | MAOBMAPTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959480-A | Polycyclic gamma-pyrone-3-carboxaldehyde derivatives | WARNER-LAMBERT COMPANY (US) | 1976-05-25 | — | — | US | disclosed |