Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19718187 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP2SRD5A2KMT2AKDM4E | |
| SCHEMBL9221702 | 0.81 | ACHE (0.50) | ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL5660492 | 0.76 | SMN1; SMN2 (0.53) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL5659127 | 0.76 | SMN1; SMN2 (0.53) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL1992671 | 0.76 | SMN1; SMN2 (0.53) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL11761484 | 0.76 | TDP1 (0.47) | ALDH1A1TDP2PTPRCKMT2AMEN1 | |
| SCHEMBL17327530 | 0.75 | TDP2 (0.62) | ALDH1A1TDP2SRD5A2TTRPTPRC | |
| SCHEMBL28135598 | 0.75 | TDP2 (0.46) | ALDH1A1TDP2SRD5A2TTRPTPRC | |
| SCHEMBL785704 | 0.74 | PBRM1 (0.58) | ALDH1A1TDP2SRD5A2TTRPTPRC | |
| SCHEMBL23617815 | 0.72 | ACHE (0.60) | ALDH1A1TDP2SRD5A2TTRPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-51125366-A | — | — | None | — | — | JP | disclosed |
| JP-S51125366-A | PROCESS FOR PREPARATION OF 1-TETRALONE- -3,7-DICARBOXYLICACID- -DIALKY LESTER | TEIJIN LTD | 1976-11-01 | — | — | JP | disclosed |