Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864242 | 0.89 | LCK (0.68) | LCKEGFRMMEACEALOX15 | |
| SCHEMBL7302581 | 0.87 | ALDH1A1 (0.43) | LCKEGFRALOX15ALDH1A1ALOX12 | |
| SCHEMBL7298903 | 0.87 | LCK (0.42) | LCKEGFRALDH1A1TP53MAPT | |
| SCHEMBL10955169 | 0.86 | LNPEP (0.51) | ALDH1A1TP53KMT2APOLBACACB | |
| SCHEMBL15275678 | 0.85 | LCK (0.52) | LCKEGFRMMEACEALOX15 | |
| SCHEMBL11850734 | 0.85 | LCK (0.53) | LCKEGFRMMEACEALOX15 | |
| SCHEMBL7291954 | 0.84 | LCK (0.50) | LCKEGFRALOX15KDM4ERECQL | |
| SCHEMBL7302573 | 0.84 | MAPT (0.42) | LCKEGFRALOX15ALDH1A1ALOX12 | |
| SCHEMBL7298898 | 0.84 | MAPT (0.42) | LCKEGFRALDH1A1TP53MAPT | |
| SCHEMBL11858343 | 0.84 | ACE (0.51) | LCKEGFRACEALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |