Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | TDO2 | P48775 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870346 | 0.89 | APLNR (0.39) | IDO1TDO2APLNR | |
| SCHEMBL31395293 | 0.83 | IDO1 (0.49) | IDO1TDO2SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL500056 | 0.78 | APLNR (0.39) | IDO1TDO2TRPC5APLNR | |
| SCHEMBL792136 | 0.77 | IDO1 (0.58) | IDO1TDO2SLC6A3CHRM1SLC6A2 | |
| SCHEMBL11867787 | 0.73 | HDAC3 (0.36) | IDO1TDO2SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9072518 | 0.71 | APLNR (0.39) | CHRM1SLC6A2CYP1A2APLNR | |
| SCHEMBL27568024 | 0.70 | APLNR (0.38) | APLNR | |
| SCHEMBL11857823 | 0.69 | APLNR (0.44) | APLNR | |
| SCHEMBL1337142 | 0.69 | PKM (0.35) | IDO1TDO2CYP1A2APLNR | |
| SCHEMBL29890715 | 0.69 | PKM (0.35) | IDO1TDO2CYP1A2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |