Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 12/20 | 0.45 |
| ▸ | AR | P10275 | 12/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SHBG | P04278 | 3/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864782 | 1.00 | PGR (0.45) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL11861831 | 0.88 | SHBG (0.58) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL11861828 | 0.88 | SHBG (0.58) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL11863792 | 0.83 | SRD5A2 (0.40) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL11863797 | 0.83 | SRD5A2 (0.40) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL11858281 | 0.75 | PGR (0.78) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL1843682 | 0.75 | PGR (0.78) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL11860406 | 0.74 | PGR (0.55) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL10477563 | 0.74 | PGR (0.41) | PGRARSLC6A4ESR1LMNA | |
| SCHEMBL11865905 | 0.74 | ESR1 (0.56) | PGRARSLC6A4ESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959322-A | Synthesis of 13-alkyl-gon-4-ones | Smith, Herchel (US) | 1976-05-25 | — | — | US | disclosed |