Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 11/20 | 0.41 |
| ▸ | AR | P10275 | 9/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | SHBG | P04278 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477545 | 0.81 | PGR (0.35) | PGRARSLC6A4ESR1SHBG | |
| SCHEMBL5925274 | 0.76 | CYP3A4 (0.55) | PGRARSLC6A4ESR1SHBG | |
| SCHEMBL10477541 | 0.76 | LMNA (0.43) | PGRARSLC6A4ESR1SHBG | |
| SCHEMBL20851724 | 0.74 | SHBG (0.41) | PGRARSLC6A4ESR1SHBG | |
| SCHEMBL20851723 | 0.74 | SHBG (0.41) | PGRARSLC6A4ESR1SHBG | |
| SCHEMBL11864782 | 0.74 | PGR (0.45) | PGRARSLC6A4ESR1SHBG | |
| SCHEMBL11864787 | 0.74 | PGR (0.45) | PGRARSLC6A4ESR1SHBG | |
| SCHEMBL11859434 | 0.73 | SLC6A4 (0.58) | PGRARSLC6A4ESR1SHBG | |
| SCHEMBL5925294 | 0.73 | SHBG (0.42) | ARESR1SHBGPOLBALDH1A1 | |
| SCHEMBL2820028 | 0.72 | PGR (0.33) | PGRARSLC6A4ESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885117-A | Process for the preparation of (Z)-17α-halovinyl steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-12-05 | — | — | US | disclosed |