Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 11/20 | 0.54 |
| ▸ | PGR | P06401 | 5/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878820 | 0.89 | HIF1A (0.56) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL11864447 | 0.88 | CYP3A4 (0.73) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL11875277 | 0.86 | NR3C1 (0.72) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL2020622 | 0.84 | HIF1A (0.73) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL13768969 | 0.84 | HIF1A (0.64) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL16017612 | 0.83 | HIF1A (0.63) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL21706395 | 0.83 | HIF1A (0.63) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL2019946 | 0.83 | HIF1A (0.61) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL12396664 | 0.82 | HIF1A (0.71) | HIF1APGRNR3C1CYP3A4AR | |
| SCHEMBL9073513 | 0.82 | HIF1A (0.71) | HIF1APGRNR3C1CYP3A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975378-A | ANTIINFLAMMATORY | SYNTEX (U.S.A.) INC. (US) | 1976-08-17 | — | — | US | disclosed |