Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.72 |
| ▸ | PGR | P06401 | 7/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | IL5 | P05113 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871492 | 0.91 | NR3C1 (0.79) | NR3C1PGRNR1I2ADORA3CNR1 | |
| SCHEMBL11872113 | 0.87 | PGR (0.72) | NR3C1PGRADORA3CYP3A4HIF1A | |
| SCHEMBL11865311 | 0.87 | PGR (0.60) | NR3C1PGRNR1I2ADORA3CNR1 | |
| SCHEMBL11865778 | 0.86 | HIF1A (0.54) | NR3C1PGRCYP3A4HIF1ALMNA | |
| SCHEMBL11321819 | 0.85 | NR3C1 (0.81) | NR3C1PGRNR1I2ADORA3CNR1 | |
| SCHEMBL11568254 | 0.85 | NR3C1 (0.81) | NR3C1PGRNR1I2ADORA3CNR1 | |
| Desonide SCHEMBL9848320 | 0.84 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA | |
| Desonide SCHEMBL1649865 | 0.84 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA | |
| Desonide SCHEMBL1650014 | 0.84 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA | |
| Desonide SCHEMBL21570018 | 0.84 | NR3C1 (1.00) | NR3C1PGRCYP3A4HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975378-A | ANTIINFLAMMATORY | SYNTEX (U.S.A.) INC. (US) | 1976-08-17 | — | — | US | disclosed |