Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21382246 | 0.87 | MAPK1 (0.46) | ALDH1A1MAPK1KDM4ENPC1MAPT | |
| SCHEMBL3656769 | 0.86 | TSHR (0.51) | ALDH1A1MAPK1KDM4ENPC1MAPT | |
| SCHEMBL6717574 | 0.86 | TSHR (0.49) | ALDH1A1MAPK1KDM4ENPC1MAPT | |
| SCHEMBL3661310 | 0.85 | KEAP1 (0.49) | ALDH1A1MAPK1KDM4ENPC1MAPT | |
| SCHEMBL7771243 | 0.81 | TSHR (0.51) | ALDH1A1MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL7455182 | 0.78 | LTB4R2 (0.45) | ALDH1A1MAPK1KDM4EMAPTLTB4R2 | |
| SCHEMBL8469252 | 0.76 | PPARG (0.42) | PPARGPPARA | |
| SCHEMBL6893551 | 0.73 | TSHR (0.47) | ALDH1A1MAPK1KDM4ENPC1MAPT | |
| SCHEMBL4081274 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL6266590 | 0.73 | SMN1; SMN2 (0.49) | ALDH1A1MAPK1KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962230-A | BACTERICIDES | SMITHKLINE & FRENCH LABORATORIES, INC. (US) | 1976-06-08 | — | — | US | disclosed |