Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4475144 | 0.86 | TSHR (0.50) | KCNN4TSHRACHELMNAHTR2A | |
| SCHEMBL28635050 | 0.86 | TSHR (0.34) | KCNN4TSHRACHELMNAKDM4E | |
| SCHEMBL8947032 | 0.79 | TSHR (0.47) | KCNN4TSHRACHELMNAGABRA1 | |
| SCHEMBL11868726 | 0.77 | ACHE (0.50) | KCNN4TSHRACHEHSD11B1GABRA1 | |
| Hydrochloric Acid SCHEMBL27874695 | 0.77 | TSHR (0.45) | KCNN4TSHRACHELMNAGABRA1 | |
| SCHEMBL4122937 | 0.76 | TSHR (0.44) | KCNN4TSHRACHELMNAGABRA1 | |
| SCHEMBL11865116 | 0.75 | TSHR (0.39) | TSHRACHEALDH1A1CYP3A4MAPK1 | |
| SCHEMBL4470543 | 0.75 | KCNN4 (0.42) | KCNN4TSHRACHELMNAHSD11B1 | |
| SCHEMBL11865649 | 0.74 | KCNN4 (0.41) | KCNN4TSHRACHELMNAHTR2A | |
| SCHEMBL31521772 | 0.74 | TSHR (0.47) | TSHRACHEGABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985766-A | ANTIMYCOTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |