SCHEMBL8947032

SCHEMBL8947032

Cc1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.47
ACHE P22303 2/20 0.47
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
ALDH1A1 P00352 5/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
TRPA1 O75762 1/20 0.35
ATM Q13315 1/20 0.35
CASR P41180 1/20 0.34
LMNA P02545 1/20 0.33
KCNN4 O15554 1/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27874695 0.97 TSHR (0.45) TSHRACHEGABRA1GABRB2ALDH1A1
Acetic Acid SCHEMBL28614085 0.87 HPGD (0.39) TSHRACHEGABRA1GABRB2ALDH1A1
SCHEMBL31521772 0.83 TSHR (0.47) TSHRACHEGABRA1GABRB2ALDH1A1
SCHEMBL11528502 0.83 TSHR (0.47) TSHRACHEGABRA1GABRB2ALDH1A1
SCHEMBL4237173 0.81 TSHR (0.45) TSHRACHEGABRA1GABRB2ALDH1A1
SCHEMBL2495517 0.81 TSHR (0.45) TSHRACHEGABRA1GABRB2ALDH1A1
SCHEMBL20840711 0.79 TSHR (0.43) TSHRACHEGABRA1GABRB2ALDH1A1
SCHEMBL11867005 0.79 KCNN4 (0.41) TSHRACHEGABRA1GABRB2ALDH1A1
SCHEMBL545083 0.78 TSHR (0.50) TSHRALDH1A1CA2TDP1CYP3A4
SCHEMBL30318973 0.78 TSHR (0.50) TSHRALDH1A1CA2TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4209653-A α-Olefin dimer isomerization using organo-halogens SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-06-24 US claimed
CN-120623022-A O-methyl chlorobenzyl production process and production system thereof 江苏鸣翔化工有限公司 2025-09-12 CN disclosed
CN-119930484-A Synthesis method of 4-methylsulfonyl toluene derivative 辽宁龙田化工科技有限公司 2025-05-06 CN disclosed
CN-114773148-B Method for synthesizing 2, 3-dichloro-1, 1-trifluoropropane and 2-chloro-1, 1-trifluoropropene 福建永晶科技股份有限公司 2024-05-28 CN disclosed
US-11760707-B2 Process for the synthesis of 2,3,3,3-tetrafluoropropene FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) 2023-09-19 US disclosed
US-11629110-B2 Process for manufacture of 2,3-dichloro-1,1,1-trifluoropropane FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) 2023-04-18 US disclosed
US-11578022-B2 Process for manufacture of 2-chloro-1,1,1-trifluoropropene FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) 2023-02-14 US disclosed
US-11572328-B2 Process for manufacture of 2,3,3,3-tetrafluoropropene FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) 2023-02-07 US disclosed
CN-111187143-B Method for synthesizing 2,3,3, 3-tetrafluoropropene and 2, 3-dichloro-1, 1, 1-trifluoropropane 福建永晶科技股份有限公司 2022-09-16 CN disclosed
CN-114773148-A Method for synthesizing 2, 3-dichloro-1, 1, 1-trifluoropropane and 2-chloro-1, 1, 1-trifluoropropene 福建永晶科技股份有限公司 2022-07-22 CN disclosed
EP-0374903-A2 Process for producing flame-retarded polymer molded articles HERCULES INCORPORATED (US) 1990-06-27 EP disclosed
US-4783562-A Process for the preparation of trichloromethyl-substituted aromatic compounds, and trichloromethyl-substituted aromatic compounds obtained in this process BAYER AKTIENGESELLSCHAFT (DE) 1988-11-08 US disclosed
EP-0150169-B1 A PROCESS FOR PREPARING SUBSTITUTED BENZOTRICHLORIDE COMPOUNDS Monsanto Company (US) 1987-11-11 EP disclosed
US-4593144-A REACTING SUBSTITUTED BENZAL CHLORIDES WITH PRECHLOROALKANE IN PRESENCE OF BASE AND PHASE TRANSFER CATALYST MONSANTO COMPANY (US) 1986-06-03 US disclosed
EP-0061029-B1 PROCESS FOR THE PREPARATION OF TRICHLOROMETHYL-SUBSTITUTED AROMATIC COMPOUNDS BAYER AG (DE) 1986-01-08 EP disclosed
EP-0150169-A2 A process for preparing substituted benzotrichloride compounds Monsanto Company (US) 1985-07-31 EP disclosed
EP-0061029-A1 Process for the preparation of trichloromethyl-substituted aromatic compounds BAYER AG (DE) 1982-09-29 EP disclosed
US-4209653-A α-Olefin dimer isomerization using organo-halogens SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-06-24 US disclosed
US-4015995-A CATALYST COMPRISING ACID-RELEASING COMPOUND AND A BASE CHEVRON RESEARCH COMPANY (US) 1977-04-05 US disclosed
US-3943084-A Method for delaying the setting of and acid-settable liquid in a terrestrial zone CHEVRON RESEARCH COMPANY (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572328-B2 Process for manufacture of 2,3,3,3-tetrafluoropropene OGFOD1, CFD, FTO TSHR 772/4885ACHE 2737/4885GABRA1 4227/4885
US-11629110-B2 Process for manufacture of 2,3-dichloro-1,1,1-trifluoropropane OGFOD1, CFD, OCIAD1 TSHR 826/4885ACHE 2706/4885GABRA1 4322/4885
US-11760707-B2 Process for the synthesis of 2,3,3,3-tetrafluoropropene OGFOD1, CFD, POF1B TSHR 982/4885ACHE 2311/4885GABRA1 4296/4885
US-11578022-B2 Process for manufacture of 2-chloro-1,1,1-trifluoropropene OGFOD1, TCOF1, FTO TSHR 1041/4885ACHE 2171/4885GABRA1 3947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.