Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | EEF2K | O00418 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858506 | 0.99 | CNR2 (0.56) | CNR2CNR1RAD52ALDH1A1LMNA | |
| SCHEMBL11861062 | 0.94 | CNR2 (0.54) | CNR2CNR1RAD52ALDH1A1ABCB1 | |
| SCHEMBL11859404 | 0.94 | RAD52 (0.54) | CNR2CNR1RAD52ALDH1A1LMNA | |
| SCHEMBL11863304 | 0.92 | ABCB1 (0.59) | CNR2CNR1RAD52ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11863224 | 0.87 | RAD52 (0.51) | CNR2CNR1RAD52ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11863213 | 0.87 | RAD52 (0.51) | CNR2CNR1RAD52ALDH1A1LMNA | |
| SCHEMBL11865791 | 0.84 | CNR2 (0.47) | CNR2CNR1RAD52 | |
| SCHEMBL11867074 | 0.84 | RAD52 (0.62) | CNR2CNR1RAD52 | |
| SCHEMBL11870415 | 0.84 | CNR2 (0.49) | CNR2CNR1RAD52 | |
| SCHEMBL11860266 | 0.83 | RAD52 (0.58) | CNR2CNR1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |