Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11870710 | 0.92 | CNR2 (0.54) | ABCB1MAPK1ALDH1A1RAD52CNR2 | |
| SCHEMBL11858506 | 0.91 | CNR2 (0.56) | ABCB1MAPK1ALDH1A1RAD52CNR2 | |
| SCHEMBL11859404 | 0.91 | RAD52 (0.54) | ABCB1MAPK1KDM5BALDH1A1RAD52 | |
| SCHEMBL11861062 | 0.86 | CNR2 (0.54) | ABCB1SMN1; SMN2ALDH1A1RAD52L3MBTL1 | |
| SCHEMBL11865693 | 0.85 | PTGS2 (0.47) | ABCB1TSHRALDH1A1RAD52KDM4E | |
| Hydrochloric Acid SCHEMBL11863224 | 0.84 | RAD52 (0.51) | ABCB1MAPK1ALDH1A1RAD52CNR2 | |
| Hydrochloric Acid SCHEMBL11863213 | 0.84 | RAD52 (0.51) | ABCB1MAPK1ALDH1A1RAD52CNR2 | |
| SCHEMBL11873319 | 0.83 | SMN1; SMN2 (0.59) | ABCB1SMN1; SMN2TSHRMAPK1NPC1 | |
| SCHEMBL11867074 | 0.82 | RAD52 (0.62) | RAD52CNR2CNR1 | |
| SCHEMBL11860266 | 0.80 | RAD52 (0.58) | RAD52CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |