Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11866100 | 0.99 | GABRA1 (0.44) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL11869269 | 0.86 | GABRA5 (0.43) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL11865163 | 0.86 | OPRK1 (0.59) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL11731072 | 0.85 | OPRK1 (0.50) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL11857891 | 0.85 | GABRA1 (0.46) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| Hydrochloric Acid SCHEMBL11870792 | 0.85 | OPRK1 (0.58) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL11875341 | 0.84 | GABRA1 (0.45) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL11862551 | 0.83 | CHRM1 (0.45) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL1810705 | 0.83 | GABRA1 (0.48) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL11867993 | 0.82 | GABRA1 (0.46) | GABRA1GABRA5GABRA2GABRB2GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992393-A | ANTIDEPRESSANTS, ANTICONVULSANTS, AND ANTIANXIETY AGENTS | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3992408-A | CHEMICAL INTERMEDIATES | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |