Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853736 | 0.90 | DRD1 (0.49) | DRD1HTR2AOPRD1KCNH2OPRM1 | |
| SCHEMBL11858464 | 0.85 | OPRD1 (0.47) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11682895 | 0.84 | KCNH2 (0.57) | HTR2AOPRD1KCNH2OPRM1OPRK1 | |
| SCHEMBL11849731 | 0.83 | OPRD1 (0.41) | OPRD1KCNH2OPRM1OPRK1SIGMAR1 | |
| SCHEMBL11783954 | 0.82 | DRD2 (0.41) | DRD1OPRD1KCNH2OPRM1SIGMAR1 | |
| SCHEMBL11681807 | 0.82 | PRCP (0.48) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11782429 | 0.82 | OPRD1 (0.41) | OPRD1KCNH2OPRM1OPRK1SIGMAR1 | |
| SCHEMBL11854306 | 0.77 | PRCP (0.41) | OPRD1KCNH2SIGMAR1PRCP | |
| SCHEMBL11851978 | 0.76 | KCNH2 (0.52) | HTR2AOPRD1KCNH2OPRM1OPRK1 | |
| SCHEMBL11882596 | 0.75 | OPRD1 (0.37) | OPRD1KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |