Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | PRCP | P42785 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682895 | 0.92 | KCNH2 (0.57) | KCNH2OPRD1SIGMAR1PRCPCHRM2 | |
| SCHEMBL11867362 | 0.81 | PRCP (0.50) | KCNH2OPRD1SIGMAR1PRCP | |
| SCHEMBL11858464 | 0.81 | OPRD1 (0.47) | KCNH2OPRD1SIGMAR1PRCP | |
| SCHEMBL11684960 | 0.80 | OPRD1 (0.57) | KCNH2OPRD1SIGMAR1PRCPOPRM1 | |
| SCHEMBL11681373 | 0.80 | OPRD1 (0.60) | KCNH2OPRD1SIGMAR1PRCPOPRM1 | |
| SCHEMBL11858736 | 0.80 | OPRD1 (0.54) | KCNH2OPRD1SIGMAR1PRCPOPRM1 | |
| SCHEMBL11863710 | 0.79 | SIGMAR1 (0.60) | OPRD1SIGMAR1OPRM1OPRK1ADRA2A | |
| SCHEMBL11857141 | 0.79 | SIGMAR1 (0.50) | KCNH2OPRD1SIGMAR1PRCPADRA2A | |
| SCHEMBL11849041 | 0.79 | OPRD1 (0.46) | KCNH2OPRD1SIGMAR1PRCPOPRM1 | |
| SCHEMBL11733261 | 0.78 | OPRD1 (0.50) | KCNH2OPRD1SIGMAR1PRCPTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | claimed |