Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11874480 | 0.87 | ALDH1A1 (0.54) | NOTUMALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL11865738 | 0.84 | ALDH1A1 (0.51) | NOTUMALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL15562974 | 0.82 | MAPT (0.55) | ALDH1A1MAPTHPGDHSD17B10MEN1 | |
| SCHEMBL11864053 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDHSD17B10MEN1 | |
| SCHEMBL15562971 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL11215817 | 0.80 | ALDH1A1 (0.52) | NOTUMALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL11864583 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL11874772 | 0.80 | LMNA (0.62) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL15562863 | 0.79 | POLB (0.58) | ALDH1A1MAPTHPGDHSD17B10MEN1 | |
| SCHEMBL11871456 | 0.79 | MAPT (0.52) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | claimed |
| EP-2882430-A1 | ANTIBACTERIAL INHIBITORS | McMaster University (CA) | 2015-06-17 | — | — | EP | claimed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | claimed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| EP-2882430-A1 | ANTIBACTERIAL INHIBITORS | McMaster University (CA) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | disclosed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | disclosed |
| US-3972905-A | FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MRPL21, Q6ZSR9, SPOUT1 | NOTUM 3246/4885ALDH1A1 3080/4885MAPT 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.