Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30310181 | 1.00 | NOTUM (0.62) | NOTUMALDH1A1CYP1A2CYP3A4CYP2A6 | |
| Hydrochloric Acid SCHEMBL27783346 | 0.98 | NOTUM (0.60) | NOTUMALDH1A1CYP1A2CYP3A4CYP2A6 | |
| Ethoxycarbonyl Group SCHEMBL27921877 | 0.82 | PTGS2 (0.50) | NOTUMALDH1A1CYP1A2CYP3A4CYP2A6 | |
| SCHEMBL28016673 | 0.81 | NOTUM (0.46) | NOTUMALDH1A1CYP3A4CYP2A6KDM4E | |
| SCHEMBL3787605 | 0.77 | TLR8 (0.72) | NOTUMALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9555 | 0.77 | NOTUM (1.00) | NOTUMALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL21408738 | 0.76 | NOTUM (0.55) | NOTUMALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL21795694 | 0.75 | NOTUM (0.75) | NOTUMALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL2670934 | 0.75 | NOTUM (0.65) | NOTUMALDH1A1KDM4EHPGDTP53 | |
| Biphenyl SCHEMBL22577775 | 0.75 | NOTUM (0.95) | NOTUMALDH1A1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112830941-A | Synthesis method of polyacid-based metal organic framework materials with different functionalities | 东北师范大学 | 2021-05-25 | — | — | CN | claimed |
| CN-101715449-A | Heterocyclic compounds and their methods of use | ABBOTT LAB | 2010-05-26 | — | — | CN | claimed |
| CN-101605542-A | Pharmaceutical compositions and methods of use thereof | ABBOTT LAB (US) | 2009-12-16 | — | — | CN | claimed |
| US-20020025477-A1 | Non-aqueous electrolytic solution and secondary battery containing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-02-28 | — | — | US | claimed |
| EP-1172878-A2 | Non-aqueous electrolytic solution and secondary battery containing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-16 | — | — | EP | claimed |
| EP-0097126-B1 | 2-(3-PYRIDYL)-1,3,4-OXADIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS BIOCIDES | CIBA-GEIGY AG (CH) | 1988-07-27 | — | — | EP | claimed |
| EP-0097126-A2 | 2-(3-Pyridyl)-1,3,4-oxadiazoles, process for their preparation and their use as biocides | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | claimed |
| JP-59007189-A | — | — | None | — | — | JP | disclosed |
| CN-115850241-A | Substituted heterocyclic compound containing alpha-ketone skeleton and application thereof | 中国药科大学 | 2023-03-28 | — | — | CN | disclosed |
| US-20220298190-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2022-09-22 | — | — | US | disclosed |
| US-11239433-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2022-02-01 | — | — | US | disclosed |
| EP-3230254-B1 | COMPOSITIONS AND METHODS FOR TREATING DISEASES AND CONDITIONS | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2021-09-22 | — | — | EP | disclosed |
| US-11072606-B2 | Compositions and methods for treating diseases and conditions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-07-27 | — | — | US | disclosed |
| US-4518601-A | INSECTICIDES, MITICIDES | CIBA GEIGY CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |
| EP-0097126-A3 | 2-(3-PYRIDYL)-1,3,4-OXADIAZOLES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS BIOCIDES | — | 1984-08-22 | — | — | EP | disclosed |
| EP-0116515-A1 | Pesticide | CIBA-GEIGY AG (CH) | 1984-08-22 | — | — | EP | disclosed |
| JP-S597189-A | 2-(3-PYRIDYL)-1,3,4-OXADIAZOLE, MANUFACTURE AND NOXIOUS ORGANISM REPELLENT | CIBA GEIGY AG | 1984-01-14 | — | — | JP | disclosed |
| EP-0097126-A2 | 2-(3-Pyridyl)-1,3,4-oxadiazoles, process for their preparation and their use as biocides | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
| EP-0097126-A2 | 2-(3-Pyridyl)-1,3,4-oxadiazoles, process for their preparation and their use as biocides | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
| EP-0097126-A2 | 2-(3-Pyridyl)-1,3,4-oxadiazoles, process for their preparation and their use as biocides | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072606-B2 | Compositions and methods for treating diseases and conditions | C1S, SLC10A1, C1R | NOTUM 2174/4885ALDH1A1 1803/4885CYP1A2 308/4885 |
| US-11239433-B2 | Organic electroluminescent materials and devices | L1CAM, OR10J3, EML4 | NOTUM 3192/4885ALDH1A1 40/4885CYP1A2 191/4885 |
| US-20220298190-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, LARP1 | NOTUM 2971/4885ALDH1A1 690/4885CYP1A2 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.