Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 11/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694561 | 0.85 | NOTUM (0.78) | NOTUMTP53KDM4EALDH1A1LMNA | |
| SCHEMBL2610163 | 0.83 | NOTUM (0.75) | NOTUMTP53KDM4EALDH1A1LMNA | |
| SCHEMBL9555 | 0.79 | NOTUM (1.00) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL21408738 | 0.78 | NOTUM (0.55) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| Water SCHEMBL27542737 | 0.78 | NOTUM (0.62) | NOTUMTP53KDM4EALDH1A1LMNA | |
| Biphenyl SCHEMBL22577775 | 0.77 | NOTUM (0.95) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL3537328 | 0.76 | NOTUM (1.00) | NOTUMTP53KDM4EALDH1A1LMNA | |
| SCHEMBL1033299 | 0.76 | NOTUM (0.63) | NOTUMKDM4EALDH1A1LMNATLR8 | |
| SCHEMBL860256 | 0.76 | NOTUM (0.64) | NOTUMTP53KDM4EALDH1A1LMNA | |
| SCHEMBL5571187 | 0.76 | NOTUM (0.91) | NOTUMKDM4EALDH1A1LMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116763814-A | Preparation method of iron supplementing preparation and iron supplementing preparation | 国家纳米科学中心 | 2023-09-19 | — | — | CN | claimed |
| CN-116769181-A | Zinc-based molecular crystal blue-green light material and preparation method thereof | 江西省科学院应用化学研究所 | 2023-09-19 | — | — | CN | claimed |
| CN-112830941-A | Synthesis method of polyacid-based metal organic framework materials with different functionalities | 东北师范大学 | 2021-05-25 | — | — | CN | claimed |
| CN-105251533-A | Preparation of complex with pyridine oxadiazole and research of catalytic activity of complex | UNIV QILU TECHNOLOGY | 2016-01-20 | — | — | CN | claimed |
| CN-105175457-A | Pyridine oxadiazole complex capable of catalyzing DHPMs (Dihydropyrimidinones) | UNIV QILU TECHNOLOGY | 2015-12-23 | — | — | CN | claimed |
| CN-105153240-A | Research of pyridine oxadiazole complex in catalyzing dihydropyrimidones | UNIV QILU TECHNOLOGY | 2015-12-16 | — | — | CN | claimed |
| US-20140301999-A1 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | DECODE GENETICS EHF (IS) | 2014-10-09 | — | — | US | claimed |
| EP-2674417-A2 | Biaryl PDE4 inhibitors for treating inflammation | Decode Genetics EHF (IS) | 2013-12-18 | — | — | EP | claimed |
| CN-103059049-A | Pure red phosphorescent crystal material as well as preparation method and application thereof | FUJIAN MATTER STRUCTURE | 2013-04-24 | — | — | CN | claimed |
| US-20120213758-A1 | BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | DeCODE Genetics enf (IS) | 2012-08-23 | — | — | US | claimed |
| US-20120183522-A1 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | DECODE GENETICS EHF (IS) | 2012-07-19 | — | — | US | claimed |
| CN-102516984-A | Orange-red phosphorescent crystal material, as well as preparation method and use thereof | FUJIAN MATTER STRUCTURE | 2012-06-27 | — | — | CN | claimed |
| EP-2222638-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | Decode Genetics EHF (IS) | 2010-09-01 | — | — | EP | claimed |
| US-20090324569-A1 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | DECODE GENETICS EHF (IS) | 2009-12-31 | — | — | US | claimed |
| US-20090136473-A1 | BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | US | claimed |
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | claimed |
| US-20020025477-A1 | Non-aqueous electrolytic solution and secondary battery containing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-02-28 | — | — | US | claimed |
| EP-1172878-A2 | Non-aqueous electrolytic solution and secondary battery containing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2002-01-16 | — | — | EP | claimed |
| CN-120048294-A | Photopolymer holographic recording medium, preparation method and application thereof | 珠海莫界科技有限公司 | 2025-05-27 | — | — | CN | disclosed |
| US-4051099-A | ISOINDOLES | CIBA-GEIGY CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136473-A1 | BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | PDE4A, PDE4B, PDE3B | NOTUM 1776/4885TP53 3957/4885PKM 1085/4885 |
| US-20120183522-A1 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | PDE4A, PDE4B, PDE3B | NOTUM 1460/4885TP53 4860/4885PKM 1344/4885 |
| US-20140301999-A1 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | PDE4A, PDE4B, PDE3B | NOTUM 1460/4885TP53 4860/4885PKM 1344/4885 |
| US-20120213758-A1 | BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | PDE4A, PDE4B, PDE3B | NOTUM 1776/4885TP53 3957/4885PKM 1085/4885 |
| US-20090324569-A1 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATORY, CARDIOVASCULAR AND CNS DISORDERS | PDE4A, PDE4B, PDE3B | NOTUM 1460/4885TP53 4860/4885PKM 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.